Liverpool fought back from a goal down to thrash the Potters 4-1 at Anfield on Tuesday and move into second place in the Premier League, one point ahead of City.
Klopp’s side host Guardiola’s men on Saturday and the German is expecting a clash to remember.
“It is [a big game]. It is for both,” he said. “I heard Pep Guardiola was in the stadium; I am not sure he watched a lot of games in the last few weeks from the stadiums of the opponents, so that’s a first sign it’s a special game and we are already looking forward to it.
“It’s a difficult game for both teams, but exciting and the best thing is it’s at Anfield. I am really looking forward to it.
“They are an outstandingly good side and we are not too bad, so it will be a nice game.”
The Reds beat City 3-0 when they last met in the top flight in March.