Woodson says Chandler, who is averaging 7.8 points and 7.6 rebounds in 13 games, is expected to play about 25 minutes.
Chandler last played on Jan. 4.
The Knicks have won all four games without him in the lineup and five straight overall.
The Bobcats got some good news as well as coach Steve Clifford says small forward Michael Kidd-Gilchrist will start after missing the last 19 games with a broken hand.
Kidd-Gilchrist, the No. 2 overall pick in the 2012 NBA draft, was averaging 9.1 points and 5.3 rebounds per game prior to his injury. Charlotte has struggled defensively since his injury.